Baker Bros. Advisors Adds $220M in Praxis Precision Medicines, Inc. ($PRAX)

Key Points

  • Baker Bros. Advisors changed its Praxis Precision Medicines, Inc. ($PRAX) stake by 55.63% last quarter, boosting to 1,753,198 shares worth $614.60 million.
  • Wall Street's consensus rating on $PRAX is Strong Buy and an average price target of $638.68.
  • $PRAX last traded around $350.56.

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Baker Bros. Advisors increased its position in Praxis Precision Medicines, Inc. ($PRAX) by 55.63% during the most recent quarter, according to its most recent Form 13F filing with the Securities and Exchange Commission. The fund owned 1,753,198 shares of Praxis Precision Medicines, Inc. after buying 626,710 shares during the quarter. Baker Bros. Advisors's holdings in Praxis Precision Medicines, Inc. were worth $614.60 million as of its most recent filing.

Praxis Precision Medicines, Inc. Stock Up 1.7%

Shares of Praxis Precision Medicines, Inc. ($PRAX) traded around $350.56 on Sunday, up 1.7% for the day.

Last price$350.56
Market cap$9.78B
Forward P/E-37.69
Beta2.78
52-week low$37.19
52-week high$392.70
50-day MA$334.30
200-day MA$303.69
Current ratio15.73
Quick ratio15.46
Debt-to-equity0

Praxis Precision Medicines, Inc. Earnings

EPS (ttm)-$12.96
Revenue (ttm)
Net margin0%
Return on equity-38.86%
Next earningsNov 9, 2026

Analysts Set New Price Targets

ConsensusStrong Buy
Average target$638.68
High target$1,201
Low target$188
Analysts covering19

About Praxis Precision Medicines, Inc.

Praxis Precision Medicines, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for central nervous system (CNS) disorders characterized by neuronal excitation-inhibition imbalance in the United States. The company's platforms include Cerebrum, a small molecule platform for CNS small molecule therapies to develop orally available precision therapies; and Solidus to discover and develop antisense oligonucleotide. It also develops ulixacaltamide, a small molecule inhibitor of T-type calcium channels that in NDA for the treatment of essential tremor; relutrigine, a small molecule, which is in NDA for the treatment of SCN2A- and SCN8A-developmental and epileptic encephalopathies (DEE), as well as in Phase 3 trial for broad DEEs; vormatrigine, a small molecule targeting the hyperexcitable state of sodium-channels in the brain that is in Phase 3 trial for the treatment of adjunctive focal epilepsy, as well as in Phase 2 trial for monotherapy focal epilepsy; and Elsunersen, a clinical-stage ASO designed to selectively decrease SCN2A gene expression, which is in Phase 3 trial for the treatment of SCN2A-DEE. In addition, the company is developing product candidates in pre-clinical trial comprising PRAX-020 to treat KCNT1; PRAX-080 that targets PCDH19 mosaic expression disorders; PRAX-090 for targeting SYNGAP1 loss-of-function; and PRAX-100 that targets SCN2A LoF mutations. It has a cooperation and license agreement with RogCon Inc.; research collaboration, option, and license agreement with Ionis Pharmaceuticals, Inc.; and research collaboration and license agreement to develop an iontophoretic transdermal patch for the delivery of ulixacaltamide. The company was formerly known as EpiPM Therapeutics, Inc. and changed its name to Praxis Precision Medicines, Inc. in October 2016. Praxis Precision Medicines, Inc. was incorporated in 2015 and is headquartered in Boston, Massachusetts.

ExchangeNasdaqGS
SectorHealthcare
IndustryBiotechnology
HeadquartersBoston, MA
CEOMr. Marcio Silva De'Souza M.B.A.
Employees168

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