Deutsche Bank Downgrades Apogee Therapeutics to Hold

Deutsche Bank set a $135 price target for Apogee Therapeutics, downgrading it to a hold rating, a 1.75% upside from the current price.

Editorial illustration for Apogee Therapeutics, Inc. (APGE)

Key Points

  • Deutsche Bank downgraded Apogee Therapeutics to a hold rating with a price target of $135 on June 23, 2026.
  • Deutsche Bank's $135 price target implies 1.75% upside from Apogee Therapeutics, Inc.'s ($APGE) current $132.68 share price.
  • Shares of NasdaqGM:APGE traded near $132.55 on Tuesday, with a market cap of approximately $9.99 billion.
  • T. Rowe Price Investment Management increased its holdings by 7,568,528 shares, now holding over 10.3 million shares.

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Deutsche Bank has downgraded Apogee Therapeutics, Inc. (NasdaqGM: APGE) to a hold rating, setting a price target of $135. This rating change was announced on June 23, 2026, by analyst David Hoang.

Analyst rating track record

Deutsche Bank vs. the S&P 500

YTD return +24.34% hypothetical
All-time return +55.74% S&P 500 +37.07%
vs. S&P 500 +18.67% ahead of the index

Hypothetical, simulated performance of disclosed positions vs. the S&P 500. Not realized profit and not investment advice. Past performance does not indicate future results. Details.

Other Institutional Activity in Apogee Therapeutics

T. Rowe Price Investment Management significantly increased its stake in Apogee Therapeutics, adding 7,568,528 shares to hold a total of 10,300,984 shares valued at about $867 million, marking a 277% increase. Meanwhile, FMR LLC also grew its position by 1,037,253 shares, bringing its total to 9,262,291 shares worth approximately $780 million, a 12.6% increase. On the other hand, Wellington Management Group reduced its holdings by 370,882 shares, now holding 4,375,703 shares valued at around $368 million, reflecting a 7.8% decrease. BlackRock, Inc. added 301,657 shares, increasing its stake by 8% to 4,085,651 shares valued at roughly $344 million.

Apogee Therapeutics, Inc. Stock Down 1.7%

Shares of Apogee Therapeutics, Inc. traded near $132.55 on Tuesday. The company has a market cap of about $9.99 billion. It is not currently profitable, with a forward P/E ratio calculated at -25.52. The stock has a 52-week low of $34.34 and a high of $133.00. Its 50-day moving average is $84.76, and the 200-day moving average is $69.38. The company maintains a strong liquidity position with a current ratio of 32.59 and a quick ratio of 32.39. Its debt-to-equity ratio stands at 0.64.

12-month forecast

$APGE price target

Past daily closes and this analyst's 12-month price target. Not investment advice.

Analysts Set New Price Targets

On June 23, 2026, Deutsche Bank downgraded Apogee Therapeutics to a hold rating, setting a price target of $135. Citigroup also downgraded the stock to hold with the same target, while UBS followed suit with a similar downgrade and target. RBC Capital maintained its hold rating with a target of $135, and Canaccord Genuity also downgraded its rating to hold with a $135.11 target. The consensus rating for Apogee Therapeutics is a strong buy, with a mean price target of $119.50 based on 16 analyst opinions.

About Apogee Therapeutics

Apogee Therapeutics, Inc. is a biotechnology company based in Waltham, Massachusetts. It focuses on developing novel biologics for treating various inflammatory and immunological conditions, including atopic dermatitis, asthma, and eosinophilic esophagitis. The company is working on several clinical-stage therapies, with Zumilokibart (APG777) in phase 2 trials for atopic dermatitis. Apogee was founded in 2022 and is led by CEO Dr. Michael Thomas Henderson.

Bottom Line

Investors are keeping a close eye on Apogee Therapeutics following Deutsche Bank's downgrade to a hold rating and the new price target of $135. While institutional investors like T. Rowe Price have significantly increased their holdings, the stock remains volatile. This analyst activity provides insights into market sentiment, although 13F filings are inherently backward-looking and may not reflect current positions.

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